TO ANSWER MY OWN QUESTION:
#include <IE.au3>
$o_IE = _IECreate ()
_IENavigate ($o_IE, "http://autos.msn.com")
_IELoadWait($o_IE)
$o_Form = _IEFormGetObjByName ($o_IE, "LeftNavForm")
$o_make = _IEFormElementGetObjByName ($o_Form, "mmMakes")
$length = _IEFormElementOptionGetCount($o_make)
For $i = 1 to $length
$blah = $o_make.options($i).text
If $blah = "Honda" Then
$o_make.options($i).selected = True
ExitLoop
Else
EndIf
Next