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FileReadToArray then Scripting.Dictionary is the best way #include <Array.au3> Local $a[11] = [1, 1, 3, 5, 6, 7, 8, 9, 10, 11, 12] Local $b[12] = [1, 2, 2, 3, 4, 5, 6, 8, 10, 12, 13, 14] Local $sda = ObjCreate("Scripting.Dictionary") Local $sdb = ObjCreate("Scripting.Dictionary") For $i In $a $sda.Item($i) Next For $i In $b $sdb.Item($i) Next For $i In $sdb If $sda.Exists($i) Then $sdb.Remove($i) Next $asd = $sdb.Keys() _ArrayDisplay($asd, "$asd")

I suspect it's one of those where you first have to create an interface, so COM stuff. Not as simple as calling dll function.

Update: -Improved Performance 64Bit: Infintiy.GlyphDesigner.64 32Bit: Infinity.GlyphDesigner

#include <Array.au3> Local $aListUnique = StringSplit("111-111,222-222,333-333,444-444,555-555,666-666,777-777",",") Local $aListExisting = StringSplit("111-111,333-333,444-444,555-555,777-777",",") _ArrayDisplay($aListUnique) _ArrayDisplay($aListExisting) Local $i, $i2 For $i = 0 to $aListUnique[0] For $i2 = 0 to $aListExisting[0] If $aListExisting[$i2] = $aListUnique[$i] Then $aListUnique[$i] = "" ExitLoop EndIf Next Next _ArrayDisplay($aListUnique) If I understand your question correctly, this would be the cumbersome method. But I get the feeling time isn't of the essence, and this would "get the job done". Any matches found in the Existing array are replaced with "".

AutoIt v3.3.12.0 has been released. Thanks to everyone involved - there's been a lot of effort in the help file, UDF library and build scripts by many under-appreciated individuals. Download it here. Complete list of changes: History